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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNE1
All Species:
23.03
Human Site:
S381
Identified Species:
38.97
UniProt:
P24864
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24864
NP_001229.1
410
47077
S381
R
A
K
K
A
M
L
S
E
Q
N
R
A
S
P
Chimpanzee
Pan troglodytes
XP_512559
393
44800
S363
R
A
K
K
A
M
L
S
E
Q
N
R
A
S
S
Rhesus Macaque
Macaca mulatta
XP_001084995
410
47103
S381
R
A
K
K
A
M
L
S
E
Q
N
R
A
S
P
Dog
Lupus familis
XP_541724
456
51105
S427
Q
A
K
K
A
I
L
S
E
Q
N
R
I
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61457
408
46968
S379
Q
A
K
K
A
I
L
S
E
Q
N
R
I
S
P
Rat
Rattus norvegicus
P39949
411
47463
S382
Q
A
K
K
A
I
L
S
E
Q
N
R
I
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507249
405
46635
E370
N
Y
L
A
M
L
D
E
V
N
Y
V
A
A
L
Chicken
Gallus gallus
P49707
407
46720
A378
Q
A
K
Q
A
I
L
A
E
Q
N
R
T
S
P
Frog
Xenopus laevis
Q91780
408
47153
E380
Y
I
N
Q
A
L
L
E
E
Q
N
R
T
S
P
Zebra Danio
Brachydanio rerio
P47794
410
46612
D382
V
H
S
Y
Q
L
V
D
I
E
S
S
Q
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54733
709
77202
A645
S
P
A
T
A
L
R
A
P
E
S
L
L
T
P
Honey Bee
Apis mellifera
XP_394802
457
51232
I408
Q
Q
R
L
V
D
E
I
P
S
T
D
T
N
E
Nematode Worm
Caenorhab. elegans
O01501
524
60567
S487
E
S
I
K
S
D
D
S
H
N
I
Q
V
Y
V
Sea Urchin
Strong. purpuratus
XP_785047
424
48468
R396
H
E
K
Q
R
L
L
R
E
A
S
C
Y
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
98.2
73.9
N.A.
78.7
79.5
N.A.
49
71.9
60.2
58.2
N.A.
28.2
38.2
24.2
44.5
Protein Similarity:
100
95.3
98.5
81.1
N.A.
88.7
90
N.A.
66.5
85.1
76.8
73.9
N.A.
39.6
55.1
41.4
60.8
P-Site Identity:
100
93.3
100
80
N.A.
80
80
N.A.
6.6
66.6
53.3
0
N.A.
13.3
0
13.3
33.3
P-Site Similarity:
100
93.3
100
93.3
N.A.
93.3
93.3
N.A.
20
93.3
66.6
26.6
N.A.
46.6
20
33.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
8
8
65
0
0
15
0
8
0
0
29
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
15
15
8
0
0
0
8
0
0
0
% D
% Glu:
8
8
0
0
0
0
8
15
65
15
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
29
0
8
8
0
8
0
22
0
0
% I
% Lys:
0
0
58
50
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
8
0
36
65
0
0
0
0
8
8
0
8
% L
% Met:
0
0
0
0
8
22
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
0
0
0
0
0
15
58
0
0
8
0
% N
% Pro:
0
8
0
0
0
0
0
0
15
0
0
0
0
0
65
% P
% Gln:
36
8
0
22
8
0
0
0
0
58
0
8
8
0
0
% Q
% Arg:
22
0
8
0
8
0
8
8
0
0
0
58
0
8
0
% R
% Ser:
8
8
8
0
8
0
0
50
0
8
22
8
0
65
15
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
8
0
22
8
0
% T
% Val:
8
0
0
0
8
0
8
0
8
0
0
8
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
8
0
0
0
0
0
0
8
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _